报告题目:SARS-CoV-2 RNA Polymerase:Structure, Function and Inhibition

报 告 人：王权

报告时间：2020.09.27 上午9:30-

报告地点：动物医学学院三楼会议室

报告人简介：Quan Wang（王权）

AssistantProfessor (tenure-track), Principal Investigator

ShanghaiTechUniversity

https://slst.shanghaitech.edu.cn/wq/main.htm

Biography

ProfessorQuan Wang is mainly engaged in the research on the structure and function ofbiomolecular complexes in the energy metabolism of microbial pathogens and genetranscription and replication systems, as well as the research and developmentof innovative drugs. In recent years, he has made breakthroughs in the study ofthe oxidative phosphorylation system supercomplex ofMycobacteriumtuberculosis(Gong et al., 2018) and the arabinosyltransferase complex inthe cell wall synthesis process (Zhang et al., 2020). During the COVID-19 pandemic,the SARS-CoV-2 RNA polymerase complex (Gao et al., 2020) and its complexstructure with the drug candidate Remdesivir (Wang et al., 2020) were analyzedin collaboration with professor Zihe Rao et al., providing an important scientificbasis for understanding the mechanism of virus replication and the developmentof antiviral drugs.

Education

2005/09-2009/07, Nankai University,Bachelor

2009/09-2014/07, Nankai University, Doctor

Experience

2014/07-2018/12, Institute of Biophysics,Chinese Academy of Sciences, Research Assistant Professor

2014/09-2015/03, Oxford University,Academic Visitor

2019/01-2019/07, Institute of Biophysics,Chinese Academy of Sciences, Research Associate Professor

2019/07-2020/01, Institute of Biophysics,Chinese Academy of Sciences, Research Professor, Principal Investigator (IBPFellow)

2020/02-Now, ShanghaiTech University,Assistant Professor（TENURE-TRACK）